Experts Continue to Defend the Approach
Many epidemiologists and public health researchers continue to support the test-negative design, noting that it has been used in studies published by some of the world's most respected medical journals.
Natalie Dean, a biostatistician at Emory University, emphasized the importance of continuing this type of research in an accompanying commentary.
As immunity patterns shift and new variants emerge, researchers need reliable ways to understand how well vaccines are performing in real-world conditions.
For many scientists, imperfect data is still better than no data at all.